Comprehensive DNA Methylation Analysis Reveals a Common Ten-Gene Methylation Signature in Colorectal Adenomas and Carcinomas

Microarray analysis of promoter hypermethylation provides insight into the role and extent of DNA methylation in the development of colorectal cancer (CRC) and may be co-monitored with the appearance of driver mutations. Colonic biopsy samples were obtained endoscopically from 10 normal, 23 adenoma...

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Pubblicato in:PLoS One
Autori principali: Patai, Árpád V., Valcz, Gábor, Hollósi, Péter, Kalmár, Alexandra, Péterfia, Bálint, Patai, Árpád, Wichmann, Barnabás, Spisák, Sándor, Barták, Barbara Kinga, Leiszter, Katalin, Tóth, Kinga, Sipos, Ferenc, Kovalszky, Ilona, Péter, Zoltán, Miheller, Pál, Tulassay, Zsolt, Molnár, Béla
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546193/
https://ncbi.nlm.nih.gov/pubmed/26291085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133836
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