Comprehensive DNA Methylation Analysis Reveals a Common Ten-Gene Methylation Signature in Colorectal Adenomas and Carcinomas

Microarray analysis of promoter hypermethylation provides insight into the role and extent of DNA methylation in the development of colorectal cancer (CRC) and may be co-monitored with the appearance of driver mutations. Colonic biopsy samples were obtained endoscopically from 10 normal, 23 adenoma...

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Udgivet i:PLoS One
Main Authors: Patai, Árpád V., Valcz, Gábor, Hollósi, Péter, Kalmár, Alexandra, Péterfia, Bálint, Patai, Árpád, Wichmann, Barnabás, Spisák, Sándor, Barták, Barbara Kinga, Leiszter, Katalin, Tóth, Kinga, Sipos, Ferenc, Kovalszky, Ilona, Péter, Zoltán, Miheller, Pál, Tulassay, Zsolt, Molnár, Béla
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546193/
https://ncbi.nlm.nih.gov/pubmed/26291085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133836
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