DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer

BACKGROUND: Colorectal cancer (CRC) development is accompanied by changes in expression for several genes; but the details of the underlying regulatory procesess remain unknown. Our aims were to assess the role of epigenetic processes in tumour formation and to identify characteristic DNA methylatio...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Kalmár, Alexandra, Péterfia, Bálint, Hollósi, Péter, Galamb, Orsolya, Spisák, Sándor, Wichmann, Barnabás, Bodor, András, Tóth, Kinga, Patai, Árpád V., Valcz, Gábor, Nagy, Zsófia Brigitta, Kubák, Vivien, Tulassay, Zsolt, Kovalszky, Ilona, Molnár, Béla
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612409/
https://ncbi.nlm.nih.gov/pubmed/26482433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1687-x
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