Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island

BACKGROUND: The septin 9 gene (SEPT9) codes for a GTP-binding protein associated with filamentous structures and cytoskeleton formation. SEPT9 plays a role in multiple cancers as either an oncogene or a tumor suppressor gene. Regulation of SEPT9 expression is complex and not well understood; however...

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Hauptverfasser: Wasserkort, Reinhold, Kalmar, Alexandra, Valcz, Gabor, Spisak, Sandor, Krispin, Manuel, Toth, Kinga, Tulassay, Zsolt, Sledziewski, Andrew Z, Molnar, Bela
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837632/
https://ncbi.nlm.nih.gov/pubmed/23988185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-398
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