CpG Island Methylation in Aberrant Crypt Foci of the Colorectum

Aberrant crypt foci (ACF) are postulated to be the earliest precursor lesion in colorectal carcinogenesis, and CpG island methylation has been described as an important molecular pathway. We therefore studied methylation in ACF from patients with familial adenomatous polyposis (FAP) or sporadic colo...

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Bibliografiske detaljer
Main Authors: Chan, Annie On-On, Broaddus, Russell R., Houlihan, Patrick S., Issa, Jean-Pierre J., Hamilton, Stanley R., Rashid, Asif
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2002
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850869/
https://ncbi.nlm.nih.gov/pubmed/12000733
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