CpG Island Methylation in Aberrant Crypt Foci of the Colorectum

Aberrant crypt foci (ACF) are postulated to be the earliest precursor lesion in colorectal carcinogenesis, and CpG island methylation has been described as an important molecular pathway. We therefore studied methylation in ACF from patients with familial adenomatous polyposis (FAP) or sporadic colo...

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Autores principales: Chan, Annie On-On, Broaddus, Russell R., Houlihan, Patrick S., Issa, Jean-Pierre J., Hamilton, Stanley R., Rashid, Asif
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2002
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Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850869/
https://ncbi.nlm.nih.gov/pubmed/12000733
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