CpG Island Methylation in Aberrant Crypt Foci of the Colorectum

Aberrant crypt foci (ACF) are postulated to be the earliest precursor lesion in colorectal carcinogenesis, and CpG island methylation has been described as an important molecular pathway. We therefore studied methylation in ACF from patients with familial adenomatous polyposis (FAP) or sporadic colo...

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Main Authors: Chan, Annie On-On, Broaddus, Russell R., Houlihan, Patrick S., Issa, Jean-Pierre J., Hamilton, Stanley R., Rashid, Asif
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2002
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850869/
https://ncbi.nlm.nih.gov/pubmed/12000733
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