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CpG Island Methylation in Aberrant Crypt Foci of the Colorectum

Aberrant crypt foci (ACF) are postulated to be the earliest precursor lesion in colorectal carcinogenesis, and CpG island methylation has been described as an important molecular pathway. We therefore studied methylation in ACF from patients with familial adenomatous polyposis (FAP) or sporadic colo...

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Auteurs principaux: Chan, Annie On-On, Broaddus, Russell R., Houlihan, Patrick S., Issa, Jean-Pierre J., Hamilton, Stanley R., Rashid, Asif
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2002
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850869/
https://ncbi.nlm.nih.gov/pubmed/12000733
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