BRAF Mutations in Aberrant Crypt Foci and Hyperplastic Polyposis

Patients with hyperplastic polyposis have multiple hyperplastic polyps (HPs) and increased risk of colorectal carcinomas. Aberrant crypt foci (ACF) are postulated to be the earliest precursor lesions in colorectal carcinogenesis. We evaluated BRAF mutations by DNA sequencing in 53 ACF from patients...

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Detalhes bibliográficos
Main Authors: Beach, Robyn, Chan, Annie On-On, Wu, Tsung-Teh, White, Jill A., Morris, Jeffrey S., Lunagomez, Simon, Broaddus, Russell R., Issa, Jean-Pierre J., Hamilton, Stanley R., Rashid, Asif
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602378/
https://ncbi.nlm.nih.gov/pubmed/15793287
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