BRAF Mutations in Aberrant Crypt Foci and Hyperplastic Polyposis

Patients with hyperplastic polyposis have multiple hyperplastic polyps (HPs) and increased risk of colorectal carcinomas. Aberrant crypt foci (ACF) are postulated to be the earliest precursor lesions in colorectal carcinogenesis. We evaluated BRAF mutations by DNA sequencing in 53 ACF from patients...

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Hlavní autoři: Beach, Robyn, Chan, Annie On-On, Wu, Tsung-Teh, White, Jill A., Morris, Jeffrey S., Lunagomez, Simon, Broaddus, Russell R., Issa, Jean-Pierre J., Hamilton, Stanley R., Rashid, Asif
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2005
Témata:
Original Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602378/
https://ncbi.nlm.nih.gov/pubmed/15793287
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