Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds

INTRODUCTION: The aim of this study was to explore changes in glomerular filtration (GFR) and renal tubular function in critically ill patients at risk of augmented renal clearance (ARC), using exogenous marker compounds. METHODS: This prospective, observational pharmacokinetic (PK) study was perfor...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Udy, Andrew A, Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Starr, Therese, Dunlop, Rachel, Wallis, Steven C, Roberts, Jason A, Lipman, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271452/
https://ncbi.nlm.nih.gov/pubmed/25432141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0657-z
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