Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds

INTRODUCTION: The aim of this study was to explore changes in glomerular filtration (GFR) and renal tubular function in critically ill patients at risk of augmented renal clearance (ARC), using exogenous marker compounds. METHODS: This prospective, observational pharmacokinetic (PK) study was perfor...

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Veröffentlicht in:Crit Care
Hauptverfasser: Udy, Andrew A, Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Starr, Therese, Dunlop, Rachel, Wallis, Steven C, Roberts, Jason A, Lipman, Jeffrey
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271452/
https://ncbi.nlm.nih.gov/pubmed/25432141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0657-z
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