Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds

INTRODUCTION: The aim of this study was to explore changes in glomerular filtration (GFR) and renal tubular function in critically ill patients at risk of augmented renal clearance (ARC), using exogenous marker compounds. METHODS: This prospective, observational pharmacokinetic (PK) study was perfor...

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Bibliografski detalji
Izdano u:Crit Care
Glavni autori: Udy, Andrew A, Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Starr, Therese, Dunlop, Rachel, Wallis, Steven C, Roberts, Jason A, Lipman, Jeffrey
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271452/
https://ncbi.nlm.nih.gov/pubmed/25432141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0657-z
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