Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds

INTRODUCTION: The aim of this study was to explore changes in glomerular filtration (GFR) and renal tubular function in critically ill patients at risk of augmented renal clearance (ARC), using exogenous marker compounds. METHODS: This prospective, observational pharmacokinetic (PK) study was perfor...

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Dettagli Bibliografici
Pubblicato in:Crit Care
Autori principali: Udy, Andrew A, Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Starr, Therese, Dunlop, Rachel, Wallis, Steven C, Roberts, Jason A, Lipman, Jeffrey
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271452/
https://ncbi.nlm.nih.gov/pubmed/25432141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0657-z
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