Effect of Obesity on the Population Pharmacokinetics of Meropenem in Critically Ill Patients

Severe pathophysiological changes in critical illness can lead to dramatically altered antimicrobial pharmacokinetics (PK). The additional effect of obesity on PK potentially increases the challenge for effective dosing. The aim of this prospective study was to describe the population PK of meropene...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Ordóñez Mejia, Jenny Lisette, Roberts, Michael S., Lipman, Jeffrey, Roberts, Jason A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958171/
https://ncbi.nlm.nih.gov/pubmed/27185798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00531-16
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