Effect of Obesity on the Population Pharmacokinetics of Fluconazole in Critically Ill Patients

Our objective was to describe the population pharmacokinetics of fluconazole in a cohort of critically ill nonobese, obese, and morbidly obese patients. Critically ill patients prescribed fluconazole were recruited into three body mass index (BMI) cohorts, nonobese (18.5 to 29.9 kg/m(2)), obese (30....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Sinnollareddy, Mahipal G., Roger, Claire, Lipman, Jeffrey, Roberts, Jason A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075058/
https://ncbi.nlm.nih.gov/pubmed/27550344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01088-16
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