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NMP-7 inhibits chronic inflammatory and neuropathic pain via block of Cav3.2 T-type calcium channels and activation of CB2 receptors

BACKGROUND: T-type calcium channels and cannabinoid receptors are known to play important roles in chronic pain, making them attractive therapeutic targets. We recently reported on the design, synthesis and analgesic properties of a novel T-type channel inhibitor (NMP-7), which also shows mixed agon...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Pain
मुख्य लेखकों: Berger, N Daniel, Gadotti, Vinicius M, Petrov, Ravil R, Chapman, Kevin, Diaz, Philippe, Zamponi, Gerald W
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271433/
https://ncbi.nlm.nih.gov/pubmed/25481027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-77
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