Aggregation Properties of the Small Nuclear Ribonucleoprotein U1-70K in Alzheimer Disease

Recent evidence indicates that U1-70K and other U1 small nuclear ribonucleoproteins are Sarkosyl-insoluble and associate with Tau neurofibrillary tangles selectively in Alzheimer disease (AD). Currently, the mechanisms underlying the conversion of soluble nuclear U1 small nuclear ribonucleoproteins...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Diner, Ian, Hales, Chadwick M., Bishof, Isaac, Rabenold, Lake, Duong, Duc M., Yi, Hong, Laur, Oskar, Gearing, Marla, Troncoso, Juan, Thambisetty, Madhav, Lah, James J., Levey, Allan I., Seyfried, Nicholas T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Neurobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271217/
https://ncbi.nlm.nih.gov/pubmed/25355317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.562959
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