Intracellular Generation of ROS by 3,5-Dimethylaminophenol: Persistence, Cellular Response, and Impact of Molecular Toxicity

Epidemiological studies have demonstrated extensive human exposure to the monocyclic aromatic amines, particularly to 3,5-dimethylaniline, and found an association between exposure to these compounds and risk for bladder cancer. Little is known about molecular mechanisms that might lead to the obser...

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Bibliographische Detailangaben
Veröffentlicht in:Toxicol Sci
Hauptverfasser: Chao, Ming-Wei, Erkekoglu, Pinar, Tseng, Chia-Yi, Ye, Wenjie, Trudel, Laura J., Skipper, Paul L., Tannenbaum, Steven R., Wogan, Gerald N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Alkylanaline Metabolites and Oxidative Toxicity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271125/
https://ncbi.nlm.nih.gov/pubmed/24973092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu127
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