SCN10A/Nav1.8 modulation of peak and late sodium currents in patients with early onset atrial fibrillation

AIMS: To test the hypothesis that vulnerability to atrial fibrillation (AF) is associated with rare coding sequence variation in the SCN10A gene, which encodes the voltage-gated sodium channel isoform Na(V)1.8 found primarily in peripheral nerves and to identify potentially disease-related mechanism...

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Détails bibliographiques
Publié dans:Cardiovasc Res
Auteurs principaux: Savio-Galimberti, Eleonora, Weeke, Peter, Muhammad, Raafia, Blair, Marcia, Ansari, Sami, Short, Laura, Atack, Thomas C., Kor, Kaylen, Vanoye, Carlos G., Olesen, Morten Salling, LuCamp, Yang, Tao, George, Alfred L., Roden, Dan M., Darbar, Dawood
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271018/
https://ncbi.nlm.nih.gov/pubmed/25053638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu170
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