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Contrasting Nav1.8 Activity in Scn10a (−/−) Ventricular Myocytes and the Intact Heart
BACKGROUND: Genome‐wide association studies have implicated variants in SCN10A, which encodes Nav1.8, as modulators of cardiac conduction. Follow‐up work has indicated the SCN10A sequence includes an intronic enhancer for SCN5A. Yet the role of the Nav1.8 protein in the myocardium itself is still un...
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| 出版年: | J Am Heart Assoc |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5210363/ https://ncbi.nlm.nih.gov/pubmed/27806966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002946 |
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