Whole-exome sequencing in familial atrial fibrillation

AIMS: Positional cloning and candidate gene approaches have shown that atrial fibrillation (AF) is a complex disease with familial aggregation. Here, we employed whole-exome sequencing (WES) in AF kindreds to identify variants associated with familial AF. METHODS AND RESULTS: WES was performed on 18...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Weeke, Peter, Muhammad, Raafia, Delaney, Jessica T., Shaffer, Christian, Mosley, Jonathan D., Blair, Marcia, Short, Laura, Stubblefield, Tanya, Roden, Dan M., Darbar, Dawood
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Clinical Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169871/
https://ncbi.nlm.nih.gov/pubmed/24727801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehu156
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