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Symptomatic response to antiarrhythmic drug therapy is modulated by a common single nucleotide polymorphism in atrial fibrillation

OBJECTIVES: This study tested the hypothesis that response to antiarrhythmic drugs (AADs) is modulated by 3 common loci associated with atrial fibrillation (AF). BACKGROUND: Recent genome wide association studies (GWAS) have identified 3 loci, on chromosomes 4q25 (near PITX2), 16q22 (in ZFHX3), and...

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Autori principali: Parvez, Babar, Vaglio, Joseph, Rowan, Shane, Muhammad, Raafia, Kucera, Gayle, Stubblefield, Tanya, Carter, Shannon, Roden, Dan, Darbar, Dawood
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411889/
https://ncbi.nlm.nih.gov/pubmed/22726630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2012.01.070
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