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Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation

OBJECTIVES: This study tested the hypothesis that two common polymorphisms in the chromosome 4q25 region that have been associated with atrial fibrillation (AF) contribute to the variable penetrance of familial AF. BACKGROUND: Although mutations in ion channels, gap junction proteins, and signaling...

詳細記述

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書誌詳細
主要な著者: Ritchie, Marylyn D, Rowan, Shane, Kucera, Gayle, Stubblefield, Tanya, Blair, Marcia, Roden, Dan M, Darbar, Dawood
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448817/
https://ncbi.nlm.nih.gov/pubmed/22818067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2012.04.030
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