Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation

OBJECTIVES: This study tested the hypothesis that two common polymorphisms in the chromosome 4q25 region that have been associated with atrial fibrillation (AF) contribute to the variable penetrance of familial AF. BACKGROUND: Although mutations in ion channels, gap junction proteins, and signaling...

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Main Authors: Ritchie, Marylyn D, Rowan, Shane, Kucera, Gayle, Stubblefield, Tanya, Blair, Marcia, Roden, Dan M, Darbar, Dawood
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448817/
https://ncbi.nlm.nih.gov/pubmed/22818067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2012.04.030
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