Common SCN10A variants modulate PR interval and heart rate response during atrial fibrillation

AIMS: SCN10A encodes the sodium channel Nav1.8 implicated by genome-wide association studies as a modulator of atrioventricular conduction (PR interval). In a cohort of patients with atrial fibrillation (AF), we examined whether there was an association between common variants in SCN10A and both the...

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Bibliografske podrobnosti
Main Authors: Delaney, Jessica T., Muhammad, Raafia, Shi, Yaping, Schildcrout, Jonathan S., Blair, Marcia, Short, Laura, Roden, Dan M., Darbar, Dawood
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Clinical Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977588/
https://ncbi.nlm.nih.gov/pubmed/24072447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/europace/eut278
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