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Modeling human development and disease in pluripotent stem cell-derived gastric organoids

Gastric diseases, including peptic ulcer disease and gastric cancer, affect 10% of the world’s population and are largely due to chronic H. pylori infection(1–3). Species differences in embryonic development and architecture of the adult stomach make animal models suboptimal for studying human stoma...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: McCracken, Kyle W., Catá, Emily M., Crawford, Calyn M., Sinagoga, Katie L., Schumacher, Michael, Rockich, Briana E., Tsai, Yu-Hwai, Mayhew, Christopher N., Spence, Jason R., Zavros, Yana, Wells, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270898/
https://ncbi.nlm.nih.gov/pubmed/25363776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13863
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