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Generating human antral and fundic gastric organoids from pluripotent stem cells

The human stomach contains two primary domains, the corpus containing fundic epithelium, and the antrum. Here we detail two methods to differentiate human pluripotent stem cells (hPSCs) into human gastric organoids (hGOs) that recapitulate both domains. The initiation of both hGOs protocols first di...

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Détails bibliographiques
Publié dans:Nat Protoc
Auteurs principaux: Broda, Taylor R., McCracken, Kyle W., Wells, James M.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7951181/
https://ncbi.nlm.nih.gov/pubmed/30470820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-018-0080-z
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