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Synthesis of aminoacylated N(6),N(6)-dimethyladenosine solid support for efficient access to hydrolysis-resistant 3′-charged tRNA mimics
RNA-amino acid and RNA-peptide conjugates that mimic charged tRNA 3′-ends are valuable substrates for structural and functional investigations of ribosomal complexes. To obtain such conjugates, most synthetic approaches that are found in the literature make use of puromycin. This well available amin...
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| Publié dans: | Bioorg Med Chem |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier Science
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270447/ https://ncbi.nlm.nih.gov/pubmed/25457127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.09.054 |
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