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The synthesis of (15)N(7)-Hoogsteen face-labeled adenosine phosphoramidite for solid-phase RNA synthesis

ABSTRACT: We have developed an efficient route for the synthesis of (15)N(7)-labeled adenosine as phosphoramidite building block for site- and atom-specific incorporation into RNA by automated solid-phase synthesis. Such labeled RNA is required for the evaluation of selected non-canonical base pair...

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Bibliographic Details
Published in:Monatsh Chem
Main Authors: Neuner, Sandro, Kreutz, Christoph, Micura, Ronald
Format: Artigo
Language:Inglês
Published: Springer Vienna 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225212/
https://ncbi.nlm.nih.gov/pubmed/28127100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-016-1882-8
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