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Facile synthesis of a 3-deazaadenosine phosphoramidite for RNA solid-phase synthesis

Access to 3-deazaadenosine (c(3)A) building blocks for RNA solid-phase synthesis represents a severe bottleneck in modern RNA research, in particular for atomic mutagenesis experiments to explore mechanistic aspects of ribozyme catalysis. Here, we report the 5-step synthesis of a c(3)A phosphoramidi...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Beilstein J Org Chem
Päätekijät: Mairhofer, Elisabeth, Fuchs, Elisabeth, Micura, Ronald
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Beilstein-Institut 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238537/
https://ncbi.nlm.nih.gov/pubmed/28144324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.250
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