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The Synthesis of Methylated, Phosphorylated, and Phosphonated 3′-Aminoacyl-tRNA(Sec) Mimics()

The twenty first amino acid, selenocysteine (Sec), is the only amino acid that is synthesized on its cognate transfer RNA (tRNA(Sec)) in all domains of life. The multistep pathway involves O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase (SepSecS), an enzyme that catalyzes the terminal chemical rea...

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Detalhes bibliográficos
Main Authors: Rigger, Lukas, Schmidt, Rachel L., Holman, Kaitlyn M., Simonović, Miljan, Micura, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010121/
https://ncbi.nlm.nih.gov/pubmed/24127424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201302188
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