Tissue Transglutaminase Promotes Serotonin-Induced AKT Signaling and Mitogenesis in Pulmonary Vascular Smooth Muscle Cells

Tissue transglutaminase 2 (TG2) is a multifunctional enzyme that cross-links proteins with monoamines such as serotonin (5-hydroxytryptamine, 5-HT) via a transglutamidation reaction, and is associated with pathophysiologic vascular responses. 5-HT is a mitogen for pulmonary artery smooth muscle cell...

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Publicat a:Cell Signal
Autors principals: Penumatsa, Krishna, Abualkhair, Shereen, Wei, Lin, Warburton, Rod, Preston, Ioana, Hill, Nicholas S., Watts, Stephanie W., Fanburg, Barry L., Toksoz, Deniz
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270091/
https://ncbi.nlm.nih.gov/pubmed/25218191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.09.002
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