NMDA-receptor antagonists block B-cell function but foster IL-10 production in BCR/CD40-activated B cells

BACKGROUND: B cells are important effectors and regulators of adaptive and innate immune responses, inflammation and autoimmunity, for instance in anti-NMDA-receptor (NMDAR) encephalitis. Thus, pharmacological modulation of B-cell function could be an effective regimen in therapeutic strategies. Sin...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Simma, Narasimhulu, Bose, Tanima, Kahlfuß, Sascha, Mankiewicz, Judith, Lowinus, Theresa, Lühder, Fred, Schüler, Thomas, Schraven, Burkhart, Heine, Martin, Bommhardt, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269920/
https://ncbi.nlm.nih.gov/pubmed/25477292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0075-5
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