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Beyond TCR Signaling: Emerging Functions of Lck in Cancer and Immunotherapy
In recent years, the lymphocyte-specific protein tyrosine kinase (Lck) has emerged as one of the key molecules regulating T-cell functions. Studies using Lck knock-out mice or Lck-deficient T-cell lines have shown that Lck regulates the initiation of TCR signaling, T-cell development, and T-cell hom...
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| Publié dans: | Int J Mol Sci |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6679228/ https://ncbi.nlm.nih.gov/pubmed/31315298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143500 |
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