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The Activity and Stability of p56Lck and TCR Signaling Do Not Depend on the Co-Chaperone Cdc37

Lymphocyte-specific protein tyrosine kinase (Lck) is a pivotal tyrosine kinase involved in T cell receptor (TCR) signaling. Because of its importance, the activity of Lck is regulated at different levels including phosphorylation of tyrosine residues, protein–protein interactions, and localization....

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Vydáno v:Int J Mol Sci
Hlavní autoři: Kowallik, Sarah, Kritikos, Andreas, Kästle, Matthias, Thurm, Christoph, Schraven, Burkhart, Simeoni, Luca
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795971/
https://ncbi.nlm.nih.gov/pubmed/33374422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010126
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