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Characterization of the Conformational Fluctuations in the Josephin Domain of Ataxin-3
As for a variety of other molecular recognition processes, conformational fluctuations play an important role in the cleavage of polyubiquitin chains by the Josephin domain of ataxin-3. The interaction between Josephin and ubiquitin appears to be mediated by the motions of α-helical hairpin that is...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4269769/ https://ncbi.nlm.nih.gov/pubmed/25517158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.008 |
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