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The solution structure of the Josephin domain of ataxin-3: Structural determinants for molecular recognition
The Josephin domain plays an important role in the cellular functions of ataxin-3, the protein responsible for the neurodegenerative Machado–Joseph disease. We have determined the solution structure of Josephin and shown that it belongs to the family of papain-like cysteine proteases, sharing the hi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1180765/ https://ncbi.nlm.nih.gov/pubmed/16020535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501732102 |
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