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The solution structure of the Josephin domain of ataxin-3: Structural determinants for molecular recognition

The Josephin domain plays an important role in the cellular functions of ataxin-3, the protein responsible for the neurodegenerative Machado–Joseph disease. We have determined the solution structure of Josephin and shown that it belongs to the family of papain-like cysteine proteases, sharing the hi...

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Hlavní autoři: Nicastro, Giuseppe, Menon, Rajesh P., Masino, Laura, Knowles, Philip P., McDonald, Neil Q., Pastore, Annalisa
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180765/
https://ncbi.nlm.nih.gov/pubmed/16020535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501732102
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