Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data

BACKGROUND: Exome or whole-genome deep sequencing of tumor DNA along with paired normal DNA can potentially provide a detailed picture of the somatic mutations that characterize the tumor. However, analysis of such sequence data can be complicated by the presence of normal cells in the tumor specime...

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Detalles Bibliográficos
Publicado en:Ann Oncol
Main Authors: Favero, F., Joshi, T., Marquard, A. M., Birkbak, N. J., Krzystanek, M., Li, Q., Szallasi, Z., Eklund, A. C.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269342/
https://ncbi.nlm.nih.gov/pubmed/25319062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdu479
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