Local intra-articular injection of rapamycin delays articular cartilage degeneration in a murine model of osteoarthritis

INTRODUCTION: Recent studies have revealed that rapamycin activates autophagy in human chondrocytes preventing the development of osteoarthritis (OA) like changes in vitro, while the systemic injection of rapamycin reduces the severity of experimental osteoarthritis in a murine model of OA in vivo....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Arthritis Res Ther
मुख्य लेखकों: Takayama, Koji, Kawakami, Yohei, Kobayashi, Makoto, Greco, Nick, Cummins, James H, Matsushita, Takehiko, Kuroda, Ryosuke, Kurosaka, Masahiro, Fu, Freddie H, Huard, Johnny
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2014
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269094/
https://ncbi.nlm.nih.gov/pubmed/25403236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0482-4
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