Local intra-articular injection of rapamycin delays articular cartilage degeneration in a murine model of osteoarthritis

INTRODUCTION: Recent studies have revealed that rapamycin activates autophagy in human chondrocytes preventing the development of osteoarthritis (OA) like changes in vitro, while the systemic injection of rapamycin reduces the severity of experimental osteoarthritis in a murine model of OA in vivo....

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Arthritis Res Ther
Autors principals: Takayama, Koji, Kawakami, Yohei, Kobayashi, Makoto, Greco, Nick, Cummins, James H, Matsushita, Takehiko, Kuroda, Ryosuke, Kurosaka, Masahiro, Fu, Freddie H, Huard, Johnny
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269094/
https://ncbi.nlm.nih.gov/pubmed/25403236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0482-4
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars