TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis

Although there has been much success in identifying genetic variants associated with common diseases using genome-wide association studies (GWAS)(1), it has been difficult to demonstrate which variants are causal and what role they play in disease. Moreover, the modest contribution these variants ma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Gregory, Adam P., Dendrou, Calliope A., Attfield, Kathrine E., Haghikia, Aiden, Xifara, Dionysia K., Butter, Falk, Poschmann, Gereon, Kaur, Gurman, Lambert, Lydia, Leach, Oliver A., Prömel, Simone, Punwani, Divya, Felce, James H., Davis, Simon J., Gold, Ralf, Nielsen, Finn C., Siegel, Richard M., Mann, Matthias, Bell, John I., McVean, Gil, Fugger, Lars
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268493/
https://ncbi.nlm.nih.gov/pubmed/22801493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11307
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