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Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank

Genetic discovery from the multitude of phenotypes extractable from routine healthcare data can transform our understanding of the human phenome and accelerate progress towards precision medicine. However, a critical question when analysing high-dimensional and heterogeneous data is how to best inte...

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Publicat a:Nat Genet
Autors principals: Cortes, Adrian, Dendrou, Calliope A., Motyer, Allan, Jostins, Luke, Vukcevic, Damjan, Dilthey, Alexander, Donnelly, Peter, Leslie, Stephen, Fugger, Lars, McVean, Gil
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580804/
https://ncbi.nlm.nih.gov/pubmed/28759005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3926
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