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D-amino acid peptide residualizing agents bearing N-hydroxysuccinimido-and maleimido- functional groups and their application for trastuzumab radioiodination
INTRODUCTION: Proteins that undergo receptor-mediated endocytosis are subject to lysosomal degradation, requiring radioiodination methods that minimize loss of radioactivity from tumor cells after this process occurs. To accomplish this, we developed the residualizing radioiodination agent N(∊)-(3-[...
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| Publicado no: | Nucl Med Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268387/ https://ncbi.nlm.nih.gov/pubmed/25240914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2014.08.007 |
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