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Coupling of a New, Active Morphine Derivative to Sepharose for Affinity Chromatography

A new, pharmacologically active morphine derivative, 6-succinylmorphine, was synthesized. The properties of this compound and evidence for its structure are presented. Succinylmorphine was covalently coupled to ethylamino-Sepharose. Morphine-Sepharose containing up to 40 μg of morphine did not block...

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Detalhes bibliográficos
Main Authors: Simon, Eric J., Dole, William P., Hiller, Jacob M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC426813/
https://ncbi.nlm.nih.gov/pubmed/4505662
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