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Coupling of a New, Active Morphine Derivative to Sepharose for Affinity Chromatography

A new, pharmacologically active morphine derivative, 6-succinylmorphine, was synthesized. The properties of this compound and evidence for its structure are presented. Succinylmorphine was covalently coupled to ethylamino-Sepharose. Morphine-Sepharose containing up to 40 μg of morphine did not block...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Simon, Eric J., Dole, William P., Hiller, Jacob M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1972
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426813/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4505662/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.7.1835
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