Dual HER2 Targeting Impedes Growth of HER2 Gene Amplified Uterine Serous Carcinoma Xenografts

PURPOSE: Uterine serous carcinoma (USC) is an aggressive subtype of endometrial cancer that commonly harbors HER2 gene amplification. We investigated the effectiveness of HER2 inhibition using lapatinib and trastuzumab in vitro and in xenografts derived from USC cell lines and USC patient derived xe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Groeneweg, Jolijn W., Hernandez, Silvia F., Byron, Virginia F., DiGloria, Celeste M., Lopez, Hector, Scialabba, Vanessa, Kim, Minji, Zhang, Ling, Borger, Darrell R., Tambouret, Rosemary, Foster, Rosemary, Rueda, Bo R., Growdon, Whitfield B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268047/
https://ncbi.nlm.nih.gov/pubmed/25294905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1647
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados