Inhibition of Notch Signaling in Combination with Paclitaxel Reduces Platinum-Resistant Ovarian Tumor Growth

Introduction: Ovarian cancer (OvCa) is the most lethal gynecologic malignancy in the United States because of chemoresistant recurrent disease. Our objective was to investigate the efficacy of inhibiting the Notch pathway with a γ-secretase inhibitor (GSI) in an OvCa patient-derived xenograft model...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Groeneweg, Jolijn W., DiGloria, Celeste M., Yuan, Jing, Richardson, William S., Growdon, Whitfield B., Sathyanarayanan, Sriram, Foster, Rosemary, Rueda, Bo R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2014
Gaiak:
Oncology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083224/
https://ncbi.nlm.nih.gov/pubmed/25072022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00171
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