Inhibition of Notch Signaling in Combination with Paclitaxel Reduces Platinum-Resistant Ovarian Tumor Growth

Introduction: Ovarian cancer (OvCa) is the most lethal gynecologic malignancy in the United States because of chemoresistant recurrent disease. Our objective was to investigate the efficacy of inhibiting the Notch pathway with a γ-secretase inhibitor (GSI) in an OvCa patient-derived xenograft model...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Groeneweg, Jolijn W., DiGloria, Celeste M., Yuan, Jing, Richardson, William S., Growdon, Whitfield B., Sathyanarayanan, Sriram, Foster, Rosemary, Rueda, Bo R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2014
Aiheet:
Oncology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083224/
https://ncbi.nlm.nih.gov/pubmed/25072022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00171
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia