Inhibition of Hedgehog Signaling Antagonizes Serous Ovarian Cancer Growth in a Primary Xenograft Model

BACKGROUND: Recent evidence links aberrant activation of Hedgehog (Hh) signaling with the pathogenesis of several cancers including medulloblastoma, basal cell, small cell lung, pancreatic, prostate and ovarian. This investigation was designed to determine if inhibition of this pathway could inhibit...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: McCann, Christopher K., Growdon, Whitfield B., Kulkarni-Datar, Kashmira, Curley, Michael D., Friel, Anne M., Proctor, Jennifer L., Sheikh, Hana, Deyneko, Igor, Ferguson, Jeanne A., Vathipadiekal, Vinod, Birrer, Michael J., Borger, Darrell R., Mohapatra, Gayatry, Zukerberg, Lawrence R., Foster, Rosemary, MacDougall, John R., Rueda, Bo R.
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2011
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226669/
https://ncbi.nlm.nih.gov/pubmed/22140510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028077
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