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A Novel Mouse Model of Advanced Diabetic Kidney Disease

Currently available rodent models exhibit characteristics of early diabetic nephropathy (DN) such as hyperfiltration, mesangial expansion, and albuminuria yet features of late DN (hypertension, GFR decline, tubulointerstitial fibrosis) are absent or require a significant time investment for full phe...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Thibodeau, Jean-Francois, Holterman, Chet E., Burger, Dylan, Read, Naomi C., Reudelhuber, Timothy L., Kennedy, Christopher R. J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267730/
https://ncbi.nlm.nih.gov/pubmed/25514595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113459
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