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A Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis

Diabetic kidney disease and atherosclerotic disease are major causes of morbidity and mortality associated with type 2 diabetes (T2D), and diabetic kidney disease is a major cardiovascular risk factor. The black and tan, brachyury (BTBR) mouse strain with leptin deficiency (Lep(ob)) has emerged as o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Am J Pathol
Hauptverfasser: Bornfeldt, Karin E., Kramer, Farah, Batorsky, Anna, Choi, Jinkuk, Hudkins, Kelly L., Tontonoz, Peter, Alpers, Charles E., Kanter, Jenny E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785558/
https://ncbi.nlm.nih.gov/pubmed/29154962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.10.012
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