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Specific minor groove solvation is a crucial determinant of DNA binding site recognition

The DNA sequence preferences of nearly all sequence specific DNA binding proteins are influenced by the identities of bases that are not directly contacted by protein. Discrimination between non-contacted base sequences is commonly based on the differential abilities of DNA sequences to allow narrow...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Harris, Lydia-Ann, Williams, Loren Dean, Koudelka, Gerald B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267663/
https://ncbi.nlm.nih.gov/pubmed/25429976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1259
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