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Specific minor groove solvation is a crucial determinant of DNA binding site recognition

The DNA sequence preferences of nearly all sequence specific DNA binding proteins are influenced by the identities of bases that are not directly contacted by protein. Discrimination between non-contacted base sequences is commonly based on the differential abilities of DNA sequences to allow narrow...

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Udgivet i:Nucleic Acids Res
Main Authors: Harris, Lydia-Ann, Williams, Loren Dean, Koudelka, Gerald B.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267663/
https://ncbi.nlm.nih.gov/pubmed/25429976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1259
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